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药物肽

Drug peptide

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Deslorelin Acetate

发布时间:2022-06-08作者:南京杰肽生物科技有限公司

CAS No.:
57773-65-5

Molecular formula:
C64H83N17O12

Molecular Weight:
1282.45

Amino acids sequence:
Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHEt

Application:
Deslorelin Acetate is a synthetic nonapeptide analogue of the natural gonadotrophin releasing hormone (GnRH) with potential antineoplastic activity. Deslorelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Continuous, prolonged administration of goserelin in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04)

Notes: For research use only

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